研究人员为植物创建了新的CRISPR基因编辑系统
Researchers Create New CRISPR Gene-Editing System for Plants

Researchers Create New CRISPR Gene-Editing System for Plants

研究人员为植物创建了新的CRISPR基因编辑系统

马里兰大学的研究人员建立了一个新的CRISPR基因编辑系统,该系统能够比以往更加成功地改变植物的DNA。

新的系统,即CRISPR-Cas12b,将使科学家能够出于各种目的有效地改变农作物,例如使它们更能抵抗疾病或害虫。以前的基因编辑系统,如CRISPR-Cas9和CRISPR-Cas12a,在科学界受到广泛关注,但不适合修改植物DNA。

"这种技术有助于提高作物产量,并在不断变化的世界中可持续地养活不断增加的人口。最后,我们正在谈论广泛的影响和公共宣传,因为我们需要弥合研究人员正在做的工作和这些影响如何影响世界的差距,”马里兰大学植物科学助理教授、CRISPR-Cas12b系统创建者益平说。

进一步影响

自从CRISPR技术首次出现以来,研究人员一直考虑用它来转基因作物。科学家已经在试验CRISPR技术,使香蕉更能抵抗一种致命的真菌,这种真菌正在破坏拉丁美洲的种植园。

然而,使用CRISPR来治疗人类疾病仍然是它最引人注目的应用。许多基因编辑生物技术公司,包括CRISPR Therapeutics(纳斯达克:CRSP)和Editas Medicine,已经在利用CRISPR- cas9技术开发用于人类的治疗方法。

Researchers from the University of Maryland have created a new CRISPR gene-editing system that can successfully modify the DNA of plants to a greater extent than was ever possible before.

The new system, referred to as CRISPR-Cas12b, would allow scientists to effectively modify crops for various purposes, such as making them more resistant to diseases or pests. Previous gene-editing systems, such as CRISPR-Cas9 and CRISPR-Cas12a, have received plenty of attention in the scientific community, but aren't as well-suited to modifying plant DNA.

"This type of technology helps increase crop yield and sustainably feed a growing population in a changing world. In the end, we are talking about broad impact and public outreach, because we need to bridge the gap between what researchers are doing and how those impacts affect the world," said Yiping Qi, assistant professor of plant science at the University of Maryland and the creator of the CRISPR-Cas12b system.

Further implications

Ever since CRISPR technology first came onto the scene, researchers have considered using it to genetically modify crops. Scientists are already experimenting with CRISPR technology to make bananas that are more resistant to a strain of deadly fungus that is ravaging plantations in Latin America.

However, using CRISPR to treat conditions in humans remains its most compelling application. Many gene-editing biotech companies, among them CRISPR Therapeutics (NASDAQ:CRSP) and Editas Medicine, are already making use of CRISPR-Cas9 technology as they develop treatments for use in humans.

Researchers from the University of Maryland have created a new CRISPR gene-editing system that can successfully modify the DNA of plants to a greater extent than was ever possible before.

马里兰大学的研究人员建立了一个新的CRISPR基因编辑系统,该系统能够比以往更加成功地改变植物的DNA。

The new system, referred to as CRISPR-Cas12b, would allow scientists to effectively modify crops for various purposes, such as making them more resistant to diseases or pests. Previous gene-editing systems, such as CRISPR-Cas9 and CRISPR-Cas12a, have received plenty of attention in the scientific community, but aren't as well-suited to modifying plant DNA.

新的系统,即CRISPR-Cas12b,将使科学家能够出于各种目的有效地改变农作物,例如使它们更能抵抗疾病或害虫。以前的基因编辑系统,如CRISPR-Cas9和CRISPR-Cas12a,在科学界受到广泛关注,但不适合修改植物DNA。

"This type of technology helps increase crop yield and sustainably feed a growing population in a changing world. In the end, we are talking about broad impact and public outreach, because we need to bridge the gap between what researchers are doing and how those impacts affect the world," said Yiping Qi, assistant professor of plant science at the University of Maryland and the creator of the CRISPR-Cas12b system.

"这种技术有助于提高作物产量,并在不断变化的世界中可持续地养活不断增加的人口。最后,我们正在谈论广泛的影响和公共宣传,因为我们需要弥合研究人员正在做的工作和这些影响如何影响世界的差距,”马里兰大学植物科学助理教授、CRISPR-Cas12b系统创建者益平说。

Further implications

进一步影响

Ever since CRISPR technology first came onto the scene, researchers have considered using it to genetically modify crops. Scientists are already experimenting with CRISPR technology to make bananas that are more resistant to a strain of deadly fungus that is ravaging plantations in Latin America.

自从CRISPR技术首次出现以来,研究人员一直考虑用它来转基因作物。科学家已经在试验CRISPR技术,使香蕉更能抵抗一种致命的真菌,这种真菌正在破坏拉丁美洲的种植园。

However, using CRISPR to treat conditions in humans remains its most compelling application. Many gene-editing biotech companies, among them CRISPR Therapeutics (NASDAQ:CRSP) and Editas Medicine, are already making use of CRISPR-Cas9 technology as they develop treatments for use in humans.

然而,使用CRISPR来治疗人类疾病仍然是它最引人注目的应用。许多基因编辑生物技术公司,包括CRISPR Therapeutics(纳斯达克:CRSP)和Editas Medicine,已经在利用CRISPR- cas9技术开发用于人类的治疗方法。